The Fujiwara-Moritani reaction has had a profound contribution in the emergence of contemporary C-H activation protocols. Despite the applicability of the traditional approach in different fields, the associated reactivity and regioselectivity issues had rendered it redundant. The revival of this exemplary reaction requires the development of a mechanistic paradigm that would have simultaneous control on both the reactivity and regioselectivity.
View Article and Find Full Text PDFThe discovery of a potent gene regulating tumorigenesis and drug resistance is of high clinical importance. is an oncogene; however, its molecular associations and role in colorectal oncogenesis are unknown. In this study, we have explored the role of gene in tumorigenesis and studied its molecular targets in colorectal cancer (CRC).
View Article and Find Full Text PDFChimpanzees (), with a dwindling population size, are distributed across sub-Saharan Africa. They are classified into two biogeographical clusters comprising of four subspecies: a western African cluster that includes and and a central/eastern African cluster that includes and . While the genetic distinctness of Nigeria-Cameroonian chimpanzees () from western chimpanzees has been known for a while, the fine structures within population has remained under-studied.
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