Publications by authors named "S Anghel"
Femtosecond laser pulses are currently regarded as an emerging and promising tool for processing wide bandgap dielectric materials across a variety of high-end applications, although the associated physical phenomena are not yet fully understood. To address these challenges, we propose an original, fully analytical model combined with Two Temperatures Model (TTM) formalism. The model is applied to describe the interaction of fs laser pulses with a typical dielectric target (e.
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- The traditional "one drug fits all" model is being challenged by pharmacogenetics, which studies how genetic differences affect individual responses to medications.
- Current clinical practices typically overlook genetic screening, leading to varied treatment outcomes for patients with the same condition.
- Integrating pharmacogenomics can help personalize treatments by revealing how genetic variations, especially in important proteins like GPCRs, influence drug efficacy and safety, paving the way for improved precision medicine.
Article Synopsis
- Eukaryotic cells make many important proteins that get moved into a special area called the endoplasmic reticulum (ER) to be folded properly.
- A special helper protein called FKBP11 works in the ER to help these proteins fold correctly, especially those that are secreted or are part of the cell membrane.
- When FKBP11 is missing or less active, some proteins don’t stay stable and could cause problems in the cell.
Background And Purpose: The TRPM8 ion channel is involved in innocuous cold sensing and has a potent anti-inflammatory action. Its activation by lower temperature or chemical agonists such as menthol and icilin induces analgesic effects, reversing hypersensitivity and reducing chronic pain. On the other hand, prostacyclin (PGI) enhances pain and inflammation by activating the IP receptors.
View Article and Find Full Text PDFNowadays, metamaterials application enjoys notoriety in fluid decontamination and pathogen annihilation, which are frequently present in polluted fluids (e.g., water, blood, blood plasma, air or other gases).
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