Publications by authors named "S Amur"
With the extensive application of baicalein in the treatment of cardiovascular and cerebrovascular diseases, its clinical and market demand has gradually expanded. But the natural yield of baicalein is very low, and it is mainly prepared by the deglycosylation of baicalin. However, the insolubility of baicalin in water significantly limits the deglycosylation of it under biocatalysis.
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- The 2019 Workshop on Recent Issues in Bioanalysis (WRIB) was held in New Orleans from April 1-5, with over 1000 attendees from various sectors, focused on topics like bioanalysis and gene therapy.
- The event spanned five days, providing a platform for discussing current challenges in bioanalysis methods such as LCMS and qPCR.
- The resulting White Paper, divided into three parts, offers key recommendations based on discussions, covering FDA guidance, ICH draft guidelines, and various topics in biomarker and gene therapy analysis.
Article Synopsis
- The 2019 Workshop on Recent Issues in Bioanalysis (WRIB) held in New Orleans attracted over 1000 professionals from various sectors, including pharmaceuticals and regulatory agencies, focusing on current bioanalysis challenges and innovations.
- The event featured extensive discussions on topics like bioanalysis methods, biomarkers, and regulatory compliance, leading to the creation of a comprehensive White Paper to guide the bioanalytical community.
- The White Paper is divided into three parts, with Part 3 specifically addressing topics such as biomarker assay validation, reagent management strategies, and gene therapy challenges, while earlier parts discuss other key regulatory recommendations and method development.
Natural drug physcion encapsulated zeolitic imidazolate framework, and their application as antimicrobial agent.
Colloids Surf B Biointerfaces
October 2019
Article Synopsis
- This study focused on loading the natural drug phycion (PHY) into metal-organic frameworks (MOFs), specifically zeolitic imidazolate frameworks (ZIFs), using a simple nano-precipitation technique.
- The resulting PHY@ZIF-8 showed a high drug loading efficiency of 88% and a capacity of 11.49%, with effective characterization performed using various analytical methods.
- Importantly, PHY@ZIF-8 demonstrated significantly improved drug release at lower pH levels and exhibited better antibacterial activity than pure PHY, suggesting its potential for treating infectious diseases.