Publications by authors named "S Ambrosii"

Article Synopsis
  • The case involves a 36-year-old woman diagnosed with a large cervical mass late in her pregnancy, leading to the development of the Kasabach-Merritt phenomenon (KMP) after delivery, characterized by severe anemia and thrombocytopenia.
  • A literature review highlighted 14 relevant articles, identifying significant risks associated with prenatal and postnatal KMP diagnosis, with a notable rate of adverse perinatal outcomes, particularly in cases where fetal hydrops was present.
  • KMP is a rare but serious condition that can evolve rapidly, even without initial signs in the fetus, and presents a substantial risk of perinatal mortality, estimated at around 50%, emphasizing the need for careful monitoring and counseling.
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Pre-eclampsia is a severe pregnancy-related complication that manifests as a syndrome with multisystem involvement and damage. It has significantly grown in frequency during the past 30 years and could be considered as one of the major causes of maternal and fetal morbidity and mortality. However, the specific etiology and molecular mechanisms of pre-eclampsia are still poorly known and could have a variety of causes, such as altered angiogenesis, inflammations, maternal infections, obesity, metabolic disorders, gestational diabetes, and autoimmune diseases.

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Placental site trophoblastic tumor (PSTT) is a very rare form of gestational trophoblastic disease (GTD) that occurs mainly in women who have a history of termination of pregnancy. It has different characteristics from other gestational trophoblastic tumors: it grows slowly, secretes low levels of beta-human chorionic gonadotropin (β-hCG), with low metastatic potential. We report a case of PSTT of a 32-year-old patient.

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