Publications by authors named "S Amat"
Six 1,8-diazabicyclo(5.4.0)undec-7-ene-based ionic liquids (ILs) linked with ethyl or propyl hydroxyl cations, coupled with thiocyanate, dicyanamide and bistriflimide anions, were synthesized through a two-step reaction: quaternization and ion exchange.
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- The bacterial pathogen, significant in both animals and humans, is linked to a variety of infections, highlighting the need to understand its genomic and metabolic features for effective control.
- Whole-genome sequencing and antimicrobial susceptibility testing were utilized to analyze 83 genomes from multiple animal hosts, revealing that the strains are not specific to hosts or body sites, indicating a broader infection potential.
- The study found conserved virulence genes and metabolic versatility in the pathogen, which may enhance its survival and competitiveness, raising concerns about its zoonotic potential and health impacts on humans and animals.
Recent evidence suggests that environmental factors experienced by sires can be transmitted through the ejaculate (seminal plasma + sperm) into the female reproductive tract, influencing fertilization, embryo development, and postnatal offspring outcomes. This concept is termed paternal programming. In rodents, sire nutrition was shown to directly alter offspring outcomes through sperm epigenetic signatures, DNA damage/oxidative stress, cytokine profiles, and/or the seminal microbiome.
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- - The study investigated how administering vasoactive intestinal polypeptide (VIP) affects inflammation and the expression of intestinal tight junction mRNA in lambs on grain-based diets, comparing two groups: one given VIP and another given saline (control).
- - Although there were no significant differences in tight junction mRNA expressions across intestinal regions, VIP-treated lambs showed increased levels of anti-inflammatory cytokines and lower lipopolysaccharide (LPS) concentrations, indicating reduced inflammation.
- - Overall, while VIP did not appear to change tight junction mRNA levels, the treatment seemed to lower inflammation by decreasing LPS levels in lambs fed grain diets.
Background: Maternal diet quality and quantity have significant impacts on both maternal and fetal health and development. The composition and function of the maternal gut microbiome is also significantly influenced by diet; however, little is known about the impact of gestational nutrient restriction on the bovine maternal microbiome during early gestation, which is a critical stage for maternal microbiome-mediated fetal programming to take place. The objective of the present study was to evaluate the impacts of diet restriction and one-carbon metabolite (OCM) supplementation during early gestation on maternal ruminal, vaginal, and blood microbiota in cattle.
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