Publications by authors named "S Alqurashi"

Background: Anorexia nervosa (AN) can significantly affect cognitive well-being. Cognitive remediation therapy (CRT) is regarded as one of the effective treatments for cognitive impairment in some mental illnesses such as schizophrenia, bipolar disorder, and attention deficit. For this reason, this systematic review and meta-analysis aim to assess the effectiveness of CRT in patients with AN.

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Article Synopsis
  • Paroxysmal nocturnal hemoglobinuria (PNH) is a rare blood disorder linked with complement-mediated hemolysis, and iptacopan, an oral factor B inhibitor, has shown promise in its treatment.
  • A systematic review analyzed multiple studies involving 197 patients, demonstrating that iptacopan significantly increases hemoglobin levels and decreases lactate dehydrogenase (LDH) levels, indicating effective management of PNH symptoms.
  • While adverse events were common (66%-90%), they were mostly mild, with serious events occurring in a small percentage (0-20%). Overall, iptacopan appears effective and has a good safety profile, warranting further research.
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  • The study investigates the clinical features, causes, and outcomes of meningitis and encephalitis in adults in Saudi Arabia, aiming to fill a knowledge gap about these serious CNS infections.* -
  • Conducted as a retrospective single-center study from March 2016 to May 2022, it revealed that most infections were caused by unidentified pathogens and that a significant portion of patients had received antibiotics before lumbar puncture.* -
  • The findings emphasized the need for timely treatment according to guidelines and suggested the creation of national biobanks to improve the understanding of meningitis and encephalitis in Saudi Arabia.*
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Myocardial perfusion imaging (MPI) provides physiologic and functional information about the heart muscle and its blood flow. Extracardiac radioactivity can interfere with visualization of the inferior wall of the myocardium, leading to poor-quality images, difficulties in interpretation, and delays in routine practice. This study aimed to identify the efficiency of having the patient consume a carbonated lemon drink to minimize the extracardiac radioactivity of Tc-sestamibi in comparison to Tc-tetrofosmin during MPI.

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  • - The meta-analysis investigates the link between diabetes mellitus (DM) and the risk of developing spontaneous bacterial peritonitis (SBP) in patients with liver cirrhosis, involving 15 studies with over 76,000 participants.
  • - Results indicate that patients with DM have a significantly higher risk of developing SBP, with hazard ratios showing a 26% and 70% increase in risk compared to non-diabetic patients.
  • - The findings highlight DM as an independent risk factor for SBP, suggesting the need for tailored preventive strategies for cirrhotic patients who also have diabetes.
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