Publications by authors named "S Alpsoy"
Pancreatic ductal adenocarcinoma (PDAC) is recognized for its aggressive nature, dismal prognosis, and a notably low five-year survival rate, underscoring the critical need for early detection methods and more effective therapeutic approaches. This research rigorously investigates the molecular mechanisms underlying PDAC, with a focus on the identification of pivotal genes and pathways that may hold therapeutic relevance and prognostic value. Through the construction of a protein-protein interaction (PPI) network and the examination of differentially expressed genes (DEGs), the study uncovers key hub genes such as CDK1, KIF11, and BUB1, demonstrating their substantial role in the pathogenesis of PDAC.
View Article and Find Full Text PDFAim: Atrial fibrillation (AF) is a rhythm disorder characterized by very rapid and disorganized atrial-derived electrical activations with uncoordinated atrial contractions. Very short periods of AF-like activity (micro-AF) may be precursors of undetected, silent episodes of atrial fibrillation. Here, we examined the relationship between natriuretic peptide concentrations and echocardiography findings in patients with micro-AF.
View Article and Find Full Text PDFEndocan may predict the presence of coronary slow flow and coronary artery disease.
Rev Assoc Med Bras (1992)
September 2024
Article Synopsis
- The study investigates the relationship between endocan levels and coronary artery disease (CAD) and coronary slow flow (CSF) in a group of 169 subjects undergoing coronary angiography.
- Both CAD and CSF patients exhibited significantly higher endocan levels compared to a control group, with similar levels between the two conditions, suggesting endocan's role in these diseases.
- Endocan levels, particularly when exceeding 450 pg/mL, are key predictors for both CAD and CSF, highlighting its potential as an important biomarker in these cardiovascular conditions.
Can the Glasgow prognostic score predict ischemic stroke in patients with infective endocarditis?
Rev Assoc Med Bras (1992)
April 2024
Objective: The Glasgow prognosis score is a simple parameter calculated using serum levels of albumin and C-reactive protein. The aim of this study was to examine whether this parameter may predict ischemic stroke in patients with infective endocarditis.
Methods: A total of 80 patients who were diagnosed with definitive infective endocarditis according to Duke criteria between 2016 and 2023 were included in the study.
A new marker of coronary collateral flow in patients presenting with acute myocardial infarction.
Eur Rev Med Pharmacol Sci
July 2023
Objective: Multimerin-2 is an adhesion substrate between pericytes and basal membranes during angiogenesis. The present study aimed to assess the relationship between serum Multimerin-2 and coronary collateral flow grade.
Patients And Methods: Between April 2022 and August 2022, 88 patients with subacute ST-elevation myocardial infarction were included in this study.