Exploring tele-speech therapy: A scoping review of interventions, applications, benefits, and challenges.

Background: Speech disorders can significantly impact communication, social interaction, and overall quality of life, affecting individuals of all ages. Telespeech therapy has emerged as an innovative solution, leveraging technology to provide accessible and effective speech interventions remotely. This approach offers flexibility and convenience, addressing barriers such as geographical limitations and scheduling conflicts.

The prognostic value of histological grade determined after neoadjuvant chemotherapy of breast cancer.

Histological grade is a validated prognostic factor of breast cancer but may show alterations following neoadjuvant chemotherapy (NACT). Its reporting after NACT is recommended by several guidelines, but evidence of its retained prognostic impact is scarce. Patients treated with NACT followed by surgery and having sufficient residual tumour for the determination of grade were analysed for the survival effects of posttreatment grade (yG).

A challenging case of Takayasu's arteritis in a young male with various manifestations and poor outcome.

A 17-year-old boy complaining of progressive dyspnea, fever, palpitations, a 22 mm Hg blood pressure difference between the 2 arms, and arm claudication. He had a history of psoriasis-like skin lesions and bronchiectasis. Echocardiography revealed a reduced left ventricular ejection fraction, severe eccentric aortic insufficiency, circumferential aortic wall thickening, and a dilated ascending aorta with severe atherosclerotic changes.

Analyzing quality of life after low anterior resection for rectal cancer.

Background: Rectal cancer is one of the most common cancers worldwide that imposes high costs on patients and the healthcare system while also having a significant impact on the patient's quality of life (QoL).

Aim: We aimed to assess the QoL of rectal cancer patients undergoing lower anterior resection (LAR) and evaluate potential confounding factors.

Methods: In this cross-sectional study, we included patients undergoing neo-adjuvant chemotherapy followed by LAR, diverting ileostomy, and adjuvant chemotherapy.

Detection of caudal type homeobox 1 () gene methylated DNA,as a stool-based diagnostic biomarker in colorectal cancer.

Colorectal cancer (CRC) is known to develop due to the accumulation of both genetic and epigenetic alterations, resulting in the conversion of intestinal epithelial cells to malignant adenocarcinoma cells. Caudal type homeobox 1 () gene is a homeobox transcription factor and a selective tumour suppressor gene that is an important factor for the development of intestinal cells. This gene plays a role in the differentiation of intestinal epithelial cells, and its expression decreases in a number of cell lines derived from CRC, which suggests that a lack of expression is a risk factor for the development of colorectal carcinoma.