Publications by authors named "S Ali Shafiee"
Article Synopsis
- Chemo-resistance is a major challenge in cancer therapy, and NRF1 and NRF2 are important in how cells handle oxidative stress, affecting tumor growth and drug resistance.
- The study examines how NRF2 functions differently in normal and cancer cells, supporting cancer survival while protecting healthy cells.
- It suggests that targeting the NRF signaling pathways could lead to new treatments that improve the effectiveness of chemotherapy against resistant tumors.
Mirror aneurysms are rare and pose therapeutic challenges, with both endovascular and microsurgical options available. Single-stage and two-stage procedures are employed, but the optimal strategy remains unclear. This systematic review and meta-analysis evaluate the efficacy and safety of different therapeutic strategies for managing mirror aneurysms.
View Article and Find Full Text PDFMetabolic-associated fatty liver disease (MAFLD) is a chronic liver disorder characterized by fatty liver disease alongside overweight or obesity and/or type 2 diabetes mellitus (T2DM). Timely intervention is crucial for a potential cure. This study aimed to investigate the effects of bilirubin, an endogenous antioxidant, on lipid metabolism and inflammation in MAFLD.
View Article and Find Full Text PDFArticle Synopsis
- - The study analyzed the amino acid composition and functional properties of protein hydrolysates from various species, identifying key amino acids like arginine, asparagine, and glutamine in significant amounts, while also assessing their antioxidant and anti-oxidative activities against substances like linoleic acid and starch.
- - The research found that protein hydrolysates exhibited desirable physico-chemical and techno-functional properties, such as good emulsification activity, foam stability, and water-holding capacity, alongside specific metrics like conductivity and viscosity of gelatin dispersion.
- - The findings suggest that protein hydrolysates could serve as effective functional ingredients in bioactive food products aimed at addressing issues such as diabetes and oxidative stress, and could potentially be used as natural preservatives