Publications by authors named "S Albertini"
This study evaluated the efficacy of the administration of different doses of equine chorionic gonadotropin (eCG; 0 IU, 200 IU, or 300 IU) at the time of the progesterone device removal in 2-year-old Nelore (Bos indicus) heifers synchronized for fixed-timed artificial insemination (FTAI). On day 0 (D0), a total of 398 heifers received 2 mg of oestradiol benzoate i.m.
View Article and Find Full Text PDFMethane emission from beef and dairy cattle combined contributes around 4.5-5.0% of total anthropogenic global methane.
View Article and Find Full Text PDFCurrently, gonadotropin products (follicle stimulating hormone, FSH, and luteinizing hormone, LH) used in animal reproduction are produced by extraction and purification from abattoir-derived pituitary glands. This method, relying on animal-derived materials, carries the potential risk of hormone contamination and pathogen transmission. Additionally, chorionic gonadotropins are extracted from the blood of pregnant mares (equine chorionic gonadotropin; eCG) or the urine of pregnant women (human chorionic gonadotropin; hCG).
View Article and Find Full Text PDFArticle Synopsis
- - The tumor microenvironment is crucial in cancer progression, but its role in Merkel cell carcinoma (MCC) is not well understood; this study analyzes cancer-associated fibroblasts (CAFs) in MCC patient-derived xenografts.
- - The research demonstrates that injecting CAFs along with MCC cells into mice accelerates tumor growth and spread, showing that CAFs cluster around blood vessels in rapidly growing tumors.
- - Findings reveal that the activity of MCC-derived CAFs is driven by the aminopeptidase A/angiotensin receptor signaling pathway, suggesting aminopeptidase A could be a valuable biomarker for MCC prognosis and potential treatment target.
Article Synopsis
- * The study explores how sT affects metastasis by altering selectin ligand binding and modifying surface molecules on MCC cells, impacting their immune recognition and ability to evade macrophage phagocytosis.
- * Targeting CD47, a surface antigen regulated by sT, shows promise in enhancing immune response against MCC cells, suggesting that combining CD47 blockade with existing immunotherapy strategies could improve treatment outcomes for MCC patients.