A Rare Case of Rosai Dorfman Destombes Disease Presenting With Lupus Nephritis and Central Nervous System Small Vessel Vasculitis.

Rosai-Dorfman-Destombes (RDD) disease is a rare syndrome characterised by benign lymphoproliferative disorder with sinus histiocytosis that presents with massive lymphadenopathy. It occurs mainly in children and young adults. It can be associated with autoimmune diseases like systemic lupus erythematosus (SLE).

Correlation Between BMI, Caries Prevalence, and Sugar-containing Beverage Intake in 6-10 Year Old Children.

Background: The beverages containing sugar are proven risk factors for obesity and dental caries. Therefore, owing to the shared risk factors, an interrelationship is suspected between BMI, sugar beverage consumption, and dental caries in children.

Aims: The present trial was carried out to assess the interrelationship between BMI, sugar beverage consumption, and dental caries in children aged 6-10 years.

Chyluria Associated With Nephrotic-Range Proteinuria.

Chyluria is the presence of chyle in the urine and is associated with some degree of proteinuria. We report two patients with chyluria who presented with milky urine, weight loss, and edema and were found to have nephrotic-range proteinuria. Although filarial antigen was detected in only one of the patients, flexible cystoscopy could demonstrate chyle efflux from the left ureter in first patient and from both the ureters in the second patient.

Indian Society for Assisted Reproduction Consensus Guidelines on Preimplantation Genetic Testing in Fertilization Clinics.

Study Question: What are the good practice guidelines for Pre implantation genetic testing applicable in INDIA?

What Is Already Known: Pre-Implantation Genetic Testing (PGT) is not new in India. It is used to identify euploid embryos for transfer, thus enabling couples to achieve a healthy pregnancy. There has been a lot of controversy surrounding PGT in the international forums; most of these debates have failed to reach a consensus on whether PGT should be offered or its concerns be validated more.

High prevalence of CFHR deletions in Indian women with pregnancy-associated hemolytic uremic syndrome.

Aim: Pregnancy-associated hemolytic uremic syndrome (P-aHUS) is an important cause of peripartum acute kidney injury. Studies from Europe have described mutations in complement regulator genes, and data in Indian patients is scarce. Hence this study used multiplex ligation-dependent probe amplification (MLPA) to identify variants in complement genes in P-aHUS patients.