Objective: Retinopathy of prematurity (ROP) is a leading cause of preventable childhood blindness in preterm infants with low birth weight. The efficacy and safety of prophylactic agents, including vitamin A, propranolol and lipids, in reducing ROP incidence remain unclear. This systematic review and meta-analysis evaluated the effectiveness and safety of these agents in preventing ROP.
View Article and Find Full Text PDFThis study investigates the optical, mechanical, and antimicrobial properties of polypropylene (PP) fibers enhanced with titanium dioxide (TiO) and zinc oxide (ZnO) nanoparticles. Using a Mach-Zehnder interferometric system, we examined the refractive indices, birefringence, and opto-mechanical behavior of blank PP, PP/TiO, and PP/ZnO nanocomposite fibers under various conditions, including different polarization orientations and during cold drawing processes. The 2D Fourier transform algorithm is employed to analyze interferometric data, enabling precise measurements of refractive index profiles and birefringence.
View Article and Find Full Text PDFTranexamic acid (TXA) is a synthetic antifibrinolytic agent that inhibits plasminogen activation, thereby reducing bleeding. The aim of this systematic review was to investigate its role in aneurysmal subarachnoid hemorrhage (SAH)-a condition indicated by bleeding between two layers of brain tissue-to stop rebleeding and improve patient outcomes. We conducted a systematic review and meta-analysis of randomized controlled trials from 1981 to 2024, focusing on the efficacy and safety of TXA in treating aneurysmal SAH (PROSPERO registration: CRD42024504834).
View Article and Find Full Text PDFThis research focused on the design and characterization of two new transition metal complexes, NiMetPhe and CuMetPhe, derived from methionine (Met) and 1,10-phenanthroline (Phe), coordinated with Ni(II) and Cu(II) ions, respectively. Structural elucidation through analytical techniques, conductivity, elemental analysis, FTIR spectra, electronic spectra, magnetic moment, mass spectra, and thermal degradation, confirmed their octahedral geometries with the formulas [Ni(Met)(Phe)(Cl)(H₂O)] and [Cu(Met)(Phe)(Cl)(H₂O)]. Thermal analysis revealed their stability and decomposition patterns, whereas density functional theory (DFT) calculations validated the structures and provided insights into quantum chemical parameters, such as highest occupied molecular orbital-lowest unoccupied molecular orbital (HOMO-LUMO) energies, molecular orbitals, and electronic distributions.
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