BMD Changes Following 2-Year Treatment of Osteoporosis by using BMK to Monitor the Dose of Bisphosphonates.

Reasons for using BMK to adjust dose for Osteoporosis patients: 1) To keep balance between bone formation and bone resorption, 2) To set balance ofboneformation to be higher than bone resorption (+10%), 3) To slightly lengthen bone life cycle. Only 127 out of 197 patients who joined the program ofusingBMKto monitor Bisphosphonate dose could complete the 2-year follow-up. The measurement ofBMK used before the treatment was compared with that ofthe 2-year follow-up by using both T-score and PR.

Observation: application and advantages of BMK in osteoporosis by monitoring the dose of antiresorptive drugs with CTx.

One of the potential applications of BMK is the dynamic measure of bone metabolism. The present study aimed to observe the dynamic response of patients' bone toward the antiresorptive drugs by using BMK in the prospective procedure. The subjects were 309 Thai women.

Effects of the treadmill walking exercise on the biochemical bone markers.

Objective: To study the effects of moderate-intensity treadmill walking exercise on the biochemical bone markers in the menstruating and menopausal women.

Study Design: Experimental study.

Setting: Department of Rehabilitation Medicine, King Chulalongkorn Memorial Hospital.

Uropathogens and empiric antibiotics for the treatment of urinary tract infections in spinal cord injured patients at rehabilitation center, Thai Red Cross Society during 2001 to 2005.

Background: Urinary tract infection (UTI) is common in spinal cord injured patients. The authors investigated the epidemiology of bacteria associated with UTI to select an appropriate antibiotic for empirical treatment of UTI before obtaining a bacterial culture.

Objective: To determine the prevalence, as well as the causative bacteria and their susceptibility pattern of urinary tract infection in spinal cord injured patients hospitalized to the Rehabilitation Center, Thai Red Cross Society, Samutprakarn, Thailand from January 2001 to December 2005.

The efficacy, safety and carry-over effect of diacerein in the treatment of painful knee osteoarthritis: a randomised, double-blind, NSAID-controlled study.

Objective: To evaluate the efficacy, safety and carry-over effect of diacerein, in comparison to piroxicam, in the treatment of Thai patients with symptomatic knee osteoarthritis (OA).

Design: This was a double-blind, randomised, piroxicam-controlled, parallel-group study. A 7-day non-steroidal anti-inflammatory drug washout period was followed by a 16-week treatment period with either diacerein 100mg/day or piroxicam 20mg/day, and an 8-week treatment-free observation period.