Publications by authors named "S Akcurin"
The Results of 16 Years of Iodization: Assessment of Iodine Deficiency Among School-age Children in Antalya, Turkey.
J Clin Res Pediatr Endocrinol
September 2020
Objective: Iodine deficiency (ID) continues to be a problem around the world. This study investigated the prevalence of ID and goiter among school-age children in the city center of Antalya, Turkey. The aim was to investigate the effect of an iodization program, which had been running for sixteen years, on nutritional iodine status in this population.
View Article and Find Full Text PDFObjective: Childhood obesity (OB) is an acknowledged global problem with increasing prevalence reported around the world. We conducted this study with the aim of determining the local trend in OB and overweight (OW) prevalence in the last decade and to observe the alteration of OB and OW prevalence by age group. An additional aim was to construct new age- and gender-specific body mass index (BMI) reference percentile charts for Turkish children living in the city center of Antalya.
View Article and Find Full Text PDFUrinary phthalate metabolite concentrations in girls with premature thelarche.
Environ Toxicol Pharmacol
April 2018
In girls, breast development before eight years of age is called "premature thelarche (PT)". There are few studies in literature that show the interaction between PT and phthalate exposure. The aim of this study was to determine the urinary levels of di-(2-ethylhexyl) phthalate (DEHP) metabolites and other phthalate metabolites in girls with PT.
View Article and Find Full Text PDFArticle Synopsis
- - Wolfram syndrome (WS) is a rare genetic disorder marked by diverse symptoms like diabetes insipidus, diabetes mellitus, optic atrophy, and hearing loss, caused by mutations in a specific gene.
- - This study examined three patients from unrelated Turkish families, revealing a variety of symptoms and ages of onset; for instance, two patients showed symptoms in childhood, while one presented with cataracts and diabetes as the initial symptoms.
- - Genetic analysis identified previously known mutations and a new variant in the WFS1 gene, highlighting the need for genetic testing to confirm WS diagnosis, especially in cases of non-autoimmune insulin-dependent diabetes.
Objective: The CYP19A1 gene product aromatase is responsible for estrogen synthesis and androgen/estrogen equilibrium in many tissues, particularly in the placenta and gonads. Aromatase deficiency can cause various clinical phenotypes resulting from excessive androgen accumulation and insufficient estrogen synthesis during the pre- and postnatal periods. In this study, our aim was to determine the clinical characteristics and CYP19A1 mutations in three patients from a large Turkish pedigree.
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