Publications by authors named "S Akabane"
Background: Laparoscopic cholecystectomy is the preferred treatment for symptomatic cholelithiasis and acute cholecystitis, with increasing applications even in severe cases. However, the possibility of postoperative endoscopic retrograde cholangiopancreatography (ERCP) to manage choledocholithiasis or biliary injuries poses significant clinical challenges. This study aimed to develop a predictive model for ERCP incidence following emergency laparoscopic cholecystectomy using advanced machine learning techniques.
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- Completion of postoperative adjuvant chemotherapy (AC) is crucial for improving the prognosis of patients with pathological stage III colorectal cancer (CRC), making it essential to identify those who may not tolerate AC.
- The study analyzed 161 patients and found that a higher volume of abdominal aortic calcification (AAC) was significantly associated with older age, male sex, hypertension, and a greater likelihood of not completing AC.
- Results indicated that while the frequency or severity of adverse events was similar between high and low AAC groups, both high AAC and older age were strong predictors of AC incompletion, suggesting that AAC could be a risk marker for assessing patients before starting AC treatment.
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- The study examines how the height of the V wave in the central venous pressure (CVP) waveform relates to the severity of tricuspid regurgitation (TR), confirming that CVP waveform variations can indicate TR severity.
- Using preoperative data from 436 patients, researchers analyzed specific CVP waveform features with statistical methods and deep learning to capture complex patterns.
- Their findings showed significant differences in certain waveform indices correlated to TR severity, with a Transformer model achieving a high accuracy of 0.97 in validating these results.
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- A 90-year-old man had advanced colon cancer treated through various endoscopic procedures and laparoscopic surgery, but a year later, a surveillance colonoscopy revealed new cancer at the site of a previous endoscopic lesion.
- The new cancer was likely caused by cancer cells from the original tumor being implanted in the ulcer created during the endoscopic procedure.
- Cancer genomic testing showed that most genetic mutations found in the new cancer matched those from the original descending colon cancer, reinforcing the idea that cells can be transferred and lead to new tumors after endoscopic interventions.
Article Synopsis
- Rectal neuroendocrine carcinomas (NECs) are rare tumors with a worse prognosis compared to common adenocarcinomas, and the role of adjuvant chemotherapy after surgery is not well-established.
- A 48-year-old woman diagnosed with rectal NEC following a laparoscopic resection received postoperative chemotherapy with irinotecan and cisplatin, showing no recurrence after three years.
- This case emphasizes the need for a combination of surgical and chemotherapy treatments in managing aggressive rectal NECs effectively.