Publications by authors named "S Ajanovic"
Article Synopsis
- The study investigates the role of meningitis in child mortality under five years old, particularly focusing on data from six sub-Saharan African countries and Bangladesh.
- It employs post-mortem minimally invasive tissue sampling (MITS) to identify the causes of death and pathogens responsible for meningitis in this age group from December 2016 to December 2023.
- Findings reveal that meningitis contributed to 7% of child deaths, with common pathogens identified being Acinetobacter baumannii and Klebsiella pneumoniae, particularly affecting neonates and infants.
Importance: The emergence of acute neurological symptoms in children necessitates immediate intervention. Although low- and middle-income countries (LMICs) bear the highest burden of neurological diseases, there is a scarcity of diagnostic and therapeutic resources. Therefore, current understanding of the etiology of neurological emergencies in LMICs relies mainly on clinical diagnoses and verbal autopsies.
View Article and Find Full Text PDFSoil-transmitted helminth (STH) infections inflict disability worldwide, especially in the poorest communities. Current therapeutic options against STHs show limited efficacy, particularly against Trichuris trichiura. The empirical management of patients coming from high-prevalence areas has been suggested for non-endemic areas.
View Article and Find Full Text PDFObjectives: We tested the hypothesis that adjunctive rosiglitazone treatment would reduce levels of circulating angiopoietin-2 (Angpt-2) and improve outcomes of Mozambican children with severe malaria.
Methods: A randomized, double-blind, placebo-controlled trial of rosiglitazone vs placebo as adjunctive treatment to artesunate in children with severe malaria was conducted. A 0.
Background: Most childhood deaths globally are considered preventable through high-quality clinical care, which includes adherence to clinical care recommendations. Our objective was to describe adherence to World Health Organization recommendations for the management of leading causes of death among children.
Methods: We conducted a retrospective, descriptive study examining clinical data for children aged 1-59 months who were hospitalized and died in a Child Health and Mortality Prevention Surveillance (CHAMPS) catchment, December 2016-June 2021.