Head shape changes following spring-cranioplasty for craniosynostosis (CS) can be difficult to predict. While previous research has indicated a connection between surgical outcomes and calvarial bone microstructure ex-vivo, there exists a demand for identifying imaging biomarkers that can be translated into clinical settings and assist in predicting these outcomes. In this study, ten parietal (8 males, age 157 ± 26 days) and two occipital samples (males, age 1066 and 1162 days) were collected from CS patients who underwent spring cranioplasty procedures.
View Article and Find Full Text PDFJ Educ Health Promot
August 2024
Background: Disease registries are one of the important steps in the development of health information systems. The aim of this study was to compare epilepsy registration systems in the United States, England, and Australia and propose a National Epilepsy Registry System for Iran.
Materials And Methods: This study was a descriptive-comparative study conducted between 2020 and 2023, which involved the following steps: identification and selected countries with advanced registry systems in the world and Identification of their characteristics and comparison with each other.
Crouzon syndrome is a congenital craniofacial disorder caused by mutations in the Fibroblast Growth Factor Receptor 2 (FGFR2). It is characterized by the premature fusion of cranial sutures, leading to a brachycephalic head shape, and midfacial hypoplasia. The aim of this study was to investigate the effect of the FGFR2 mutation on the microarchitecture of cranial bones at different stages of postnatal skull development, using the FGFR2 mouse model.
View Article and Find Full Text PDFSpring-assisted surgery is a popular option for the treatment of non-syndromic craniosynostosis. The main drawback of this procedure is the need for a second surgery for spring removal, which could be avoided if a distractor material could be metabolised over time. Iron-Manganese alloys (FeMn) have a good trade-off between degradation rate and strength; however, their biocompatibility is still debated.
View Article and Find Full Text PDFClimate disruptions have prompted institutions to invest in zero-emissions technologies, in recent years. As a result, the transportation sector has witnessed a shift from internal combustion engines to electric. Several public transport companies have initiated the "Zero-emissions" project to introduce alternatives to diesel in their bus service.
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