Publications by authors named "S Aghayeva"
Aim Of The Study: Sarcoidosis is characterized by noncaseating granulomas that can affect multiple organs. Due to the lack of prospective studies regarding treatment of hepatic sarcoidosis with ursodeoxycholic acid (UDCA), we set out to evaluate its effects in a single-center, open-label, prospective, pre-post study.
Material And Methods: A total of 10 patients were screened from August 2018 to July 2020; seven met the criteria and were enrolled.
Article Synopsis
- This study addresses the need for effective therapeutic strategies against Clostridium septicum, a bacterium linked to gas gangrene and colorectal tumors, by developing a novel vaccine using advanced proteomics and reverse vaccinology techniques.
- Researchers identified key antigenic membrane proteins from the bacterium and created a chimeric subunit vaccine that includes immunogenic epitopes alongside immune-modulating components, enhancing its potential effectiveness.
- The results showed that the chimeric vaccine constructs, especially V1, demonstrated strong interaction with immune system components, suggesting a promising avenue for triggering robust immune responses against C. septicum infections.
The purpose of this study was to identify potential novel drug targets for Bacteroides fragilis infections using bioinformatics techniques, such as subtractive and comparative genomics. Bacteroides fragilis is a frequently isolated anaerobic pathogen, particularly in the human digestive tract, where its pathogenesis and persistence are influenced by various virulence factors. By understanding these factors, the study aims to explore alternative therapeutic strategies and provide insights for the development of treatments against B.
View Article and Find Full Text PDFZinc oxide nanoparticles have wide range biological, biomedical and environmental applications. However, traditional nanofabrication of ZnONPs uses various toxic chemicals and organic solvents which limit their bio-applications. To overcome this hurdle, Bauhinia variegata derived buds extract was utilized to fabricate ZnONPs.
View Article and Find Full Text PDFPerinatal outcomes of emergency and elective cervical cerclages.
Eur J Obstet Gynecol Reprod Biol X
March 2024
Objective: This study aims to compare the perinatal outcomes of emergency and elective cervical cerclages.
Material And Methods: This retrospective study included a total of 247 patients, with a total of 142 emergency (with a history of mid-trimester miscarriage or vaginal delivery of < 34 weeks and cervical length < 25 mm) and 105 electives cerclage patients (with painless cervical dilation and cervical length <25 mm) who had cerclage with the vaginal cervical McDonald technique between 1.1.