Publications by authors named "S Aeschlimann"
Article Synopsis
- - The study focuses on Trypanosoma brucei, a parasitic protozoan, specifically examining the tripartite attachment complex (TAC) that links its mitochondrial genome to the flagellum's basal body.
- - Central to the TAC is the interaction between the outer membrane protein TAC60 and the inner membrane protein p166, which is essential for proper mitochondrial genome segregation during cell division.
- - Researchers used various analytical techniques to identify that the binding between TAC60 and p166 is mainly driven by hydrophobic interactions rather than electrostatic ones, revealing important structural details of this contact site.
Correction for 'Water adsorption lifts the (2 × 1) reconstruction of calcite(104)' by Jonas Heggemann , , 2024, , 21365-21369, https://doi.org/10.1039/D3CP01408H.
View Article and Find Full Text PDFBackground: Visual snow syndrome is a disorder characterized by the combination of typical perceptual disturbances. The clinical picture suggests an impairment of visual filtering mechanisms and might involve primary and secondary visual brain areas, as well as higher-order attentional networks. On the level of cortical oscillations, the alpha rhythm is a prominent EEG pattern that is involved in the prioritisation of visual information.
View Article and Find Full Text PDFPurpose Of Review: Visual snow syndrome (VSS) is a disorder characterized by persistent visual disturbances, including the visual snow phenomenon, palinopsia, heightened perception of entoptic phenomena, impaired night vision, and photophobia. The purpose of this review is to provide an update on recent findings over the past 18 months in VSS research and to summarize the current state of treatment approaches.
Recent Findings: Electrophysiological studies have revealed cortical hyperresponsivity in visual brain areas, imaging studies demonstrated microstructural and functional connectivity alterations in multiple cortical and thalamic regions and investigated glutamatergic and serotoninergic neurotransmission.
Article Synopsis
- - The tripartite attachment complex (TAC) in trypanosomes helps ensure the accurate separation of their single mitochondrial genome during cell division by linking it to the flagella's basal bodies.
- - A model of the TAC’s molecular structure shows how its eight key components connect the flagella’s base with the mitochondrial DNA across membranes.
- - The study also covers how TAC components are imported into mitochondria, assembled, and compares the TAC's function with DNA segregation mechanisms in other organisms, highlighting shared principles.