[Two cases of tubular adenoma of the breast].

Two rare cases of a tubular adenoma of the breast are reported, together with a clinicopathological review of the pertinent literature. Only 14 cases of this histological type have so far been reported in Japan. Both patients were single women aged 22 and 34 years, respectively.

[Clinical studies on the transference of cephem-type antibiotics into bile and gallbladder tissues with special reference to cefotiam and cefmenoxime].

Cefotiam (CTM) and cefmenoxime (CMX) were studied for their serum concentrations and transference into bile in patients with PTCD or T-tube. One gram of CTM or either 1 g or 2 g of CMX was administered by an intravenous drip infusion for over 30 minutes. These drugs were also studied for their serum concentrations, bile concentrations, and tissue concentrations in the walls of the gallbladder of patients operated on for cholelithiasis.