Publications by authors named "S Adelman"
Article Synopsis
- Researchers are focusing on improving separation techniques in chemistry to find more sustainable alternatives to traditional methods, like liquid-liquid extraction, which are important for both basic and applied chemistry.! -
- The challenge lies in exploring a wide array of experimental conditions to optimize these separation procedures, but advancements in AI and robotics can help streamline this process.! -
- By applying Bayesian Optimization and robotic experiments, the study demonstrated a 74% reduction in experimental efforts needed to identify optimal conditions for liquid-liquid extraction of thorium, leading to significant time and cost savings as well as reduced human exposure to radioactive materials.!
Background: Amlitelimab, a fully human nondepleting mAb targeting OX40 ligand on antigen-presenting cells, could prevent T-cell-driven inflammation seen in atopic dermatitis (AD).
Objective: This trial evaluated the efficacy and safety of amlitelimab in adults with AD.
Methods: In this 2-part, phase 2b, randomized, double-blinded placebo-controlled trial (ClinicalTrials.
Article Synopsis
- There is a need for better animal models to study meibomian gland dysfunction (MGD) and evaporative dry eye disease (EDED), leading researchers to evaluate Awat2 knockout (KO) mice for this purpose.
- The study involved various tests on both wildtype and Awat2 KO mice, including ocular examinations, lipid analysis, and gene expression assessments.
- Results showed that Awat2 KO mice exhibited characteristics similar to human MGD and EDED, such as corneal issues and impaired meibum secretion, making them suitable for testing new treatments.
Recent advances enabled the discovery of heterometallic molecules for many metals: main group, d-block, lanthanides, and some actinides (U, Th). These complexes have at least two different metals joined by bridging ligands or by direct metal-metal bonding interactions. They are attractive because they can enable chemical cooperativity between metals from different parts of the periodic table.
View Article and Find Full Text PDFAutism spectrum disorder (ASD) affects up to 1 in 36 children in the United States. It is a heterogeneous neurodevelopmental disorder with life-long consequences. Patients with ASD and folate pathway abnormalities have demonstrated improved symptoms after treatment with leucovorin (folinic acid), a reduced form of folate.
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