Publications by authors named "S Adamo"
Article Synopsis
- * Researchers engineered N. oceanica using a specific strain (LP-tdTomato) to enhance ketocarotenoid production by introducing a key enzyme (CrBKT) from another alga, resulting in significant increases in carotenoid levels and a noticeable orange/red coloration in the cultures.
- * Optimal production of canthaxanthin and ketocarotenoids was achieved at lower light intensity (150 µmol m s),
Article Synopsis
- Researchers and activists use data to show how environmental problems and benefits affect different groups of people unfairly, often related to race and income.
- Satellite data can help fill in gaps in understanding these issues better than old methods, but not much is known about its full impact yet.
- A review found 81 studies using satellite data in the U.S. from 2000 to 2022, which showed that areas with more pollution and less green space often have worse health problems, pointing to the need for changes in policies to help those affected.
Article Synopsis
- Tissue-resident memory CD8 T cells play a crucial role in protecting the body against various pathogens.
- A study by Buquicchio et al. explores the unique epigenomic features of virus-specific CD8 T cell subsets.
- The research reveals both shared and organ-specific regulatory factors that influence how these T cells differentiate and respond to infections.
Mucosal-associated invariant T (MAIT) cells are unconventional T cells that recognize microbial riboflavin pathway metabolites presented by evolutionarily conserved MR1 molecules. We explored the human MAIT cell compartment across organ donor-matched blood, barrier, and lymphoid tissues. MAIT cell population size was donor dependent with distinct tissue compartmentalization patterns and adaptations: Intestinal CD103 resident MAIT cells presented an immunoregulatory CD39CD27 profile, whereas MAIT cells expressing NCAM1/CD56 dominated in the liver and exhibited enhanced effector capacity with elevated response magnitude and polyfunctionality.
View Article and Find Full Text PDFChalcones induce apoptosis, autophagy and reduce spreading in osteosarcoma 3D models.
Biomed Pharmacother
October 2024
Osteosarcoma is the most common primary bone malignancy with a challenging prognosis marked by a high rate of metastasis. The limited success of current treatments may be partially attributed to an incomplete understanding of osteosarcoma pathophysiology and to the absence of reliable in vitro models to select the best molecules for in vivo studies. Among the natural compounds relevant for osteosarcoma treatment, Licochalcone A (Lic-A) and chalcone derivatives are particularly interesting.
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