Publications by authors named "S Acevedo-Gallegos"
Article Synopsis
- - Preeclampsia (PE) is a complex pregnancy disorder characterized by high blood pressure and protein in urine, posing risks to mothers and their babies; its underlying mechanisms involve abnormal placentation and systemic responses.
- - The condition is driven by inadequate placental development, leading to hypoxia and the release of anti-angiogenic factors, which cause endothelial dysfunction and increased inflammation; genetic factors also play a crucial role.
- - Despite some promising therapeutic strategies targeting oxidative stress and inflammation, effective prevention and treatments for PE are still lacking, emphasizing the need for ongoing research in understanding and managing the disorder.
Article Synopsis
- Congenital uterine anomalies can impact reproductive capabilities, and uterus transplantation (UTx) is a potential solution for women dealing with absolute uterine factor infertility, but there are currently no standardized management protocols for these cases.
- A literature review of 36 reports highlighted 55 pregnancies and 38 live births following UTx, with living donor transplants showing higher success rates, but also noted common complications such as miscarriage and pre-eclampsia.
- The study emphasizes the need for more research to refine UTx procedures and improve outcomes for both mothers and newborns, focusing on donor and recipient characteristics.
Placental pathology lesions: International Society for Ultrasound in Obstetrics and Gynecology vs Society for Maternal-Fetal Medicine fetal growth restriction definitions.
Am J Obstet Gynecol MFM
August 2024
Background: Research on the definition of fetal growth restriction (FGR) has focused on predicting adverse perinatal outcomes. A significant limitation of this approach is that the individual outcomes of interest could be related to the condition and the treatment. Evaluation of outcomes that reflect the pathophysiology of FGR may overcome this limitation.
View Article and Find Full Text PDFObjective: To determine the individual learning curves for cordocentesis in a low-cost simulator for maternal-fetal medicine (MFM) fellows.
Methods: This observational, descriptive, educational, and prospective study was performed from July through November 2022. After an introductory course based on a standardized technique for cordocentesis, each second-year MFM fellow who accepted to participate in the study performed this procedure using a low-cost simulation model, and experienced operators supervised the cordocenteses.
Abdominal circumference growth velocity as a predictor of adverse perinatal outcomes in small-for-gestational-age fetuses.
J Matern Fetal Neonatal Med
December 2023
Objective: To assess the predictive value of abdominal circumference growth velocity (ACGV) between the second and third trimesters to predict adverse perinatal outcomes in a cohort of small-for-gestational-age fetuses without evidence of placental insufficiency (i.e. fetal growth restriction).
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