Publications by authors named "S Abele"
Article Synopsis
- Management decisions in wildlife conservation should consider both habitat selection and demographic performance, as habitat selection alone may not reflect true species viability.
- This study focuses on the greater sage-grouse to illustrate how mapping habitat selection against survival rates can reveal important mismatches and trade-offs throughout different reproductive life stages.
- By integrating demographic measures into habitat management, conservation efforts can be more effectively tailored to enhance species survival and resource allocation, particularly during critical life stages.
Solving problems in a technical system usually requires people to understand its functioning on different levels of abstraction (i.e., goals, functions, components, characteristics) that are connected via means-ends links.
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- Chloride channel accessory 2 (CLCA2) is a protein that helps keratinocytes stick together and survive when faced with high salt levels, and it's important for their function in the nucleus.
- The study reveals that CLCA2 is transported to the nucleus through extracellular vesicles, where it helps regulate cell behavior by interacting with β-catenin, influencing the expression of specific genes.
- Importantly, RNA binding protein 3 works alongside nuclear CLCA2, indicating a significant role for these proteins in skin health and their potential interaction during stress responses.
Adeno-associated viruses (AAVs) represent highly attractive gene therapy vectors and potent research tools for the modulation of gene expression in animal models or difficult-to-transfect cell cultures. Engineered variants, comprising chimeric, mutated, or peptide-inserted capsids, have strongly broadened the utility of AAVs by altering cellular tropism, enabling immune evasion, or increasing transduction efficiency. In this work, the performance of 50 of the most used, predominantly published, AAVs was compared on several primary cells, cell lines, and induced pluripotent stem cell-derived models from different organs, including the adipose tissue, liver, lung, brain, and eyes.
View Article and Find Full Text PDFProduction of value-added outputs from biomass residues represents an opportunity to increase the supply of renewable energy in Ethiopia. Particularly, agroforestry could provide biomass residues for improved bioenergy products. The aim of this study was to characterize the interest of growers to provide biomass residues to a hypothetical biomass feedstock market.
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