Publications by authors named "S Abate"

Article Synopsis
  • The study investigates healthcare professionals' attitudes towards family engagement in the ICU, highlighting inconsistencies in current practices and the lack of research in this area for adult patients.
  • Data were collected from 90 healthcare professionals using the FINC-NA questionnaire, revealing that attitudes towards family engagement varied by professional role, with physicians showing the most positive views.
  • The findings suggest that improving family engagement requires targeted interventions, specialized training, and supportive policies to foster positive attitudes among healthcare providers and create a culture of partnership with patients' families.
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Article Synopsis
  • Malnutrition is a significant public health problem that negatively affects clinical outcomes in ICU patients, particularly in developing regions like Sub-Saharan Africa.
  • A study involving 436 ICU patients found a 47.9% rate of 30-day mortality, with malnourished patients having a 40% higher risk of death compared to those who are well-nourished.
  • Well-established tools like MUST, SGA, and NUTRIC effectively assess nutritional status and can predict mortality outcomes in critically ill patients.
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Despite national efforts, gaps persist in Ethiopian perioperative care. This reflexive thematic analysis aimed to investigate the contextual challenges faced in delivering perioperative care. In-depth interviews were conducted with 20 healthcare professionals, including anesthetists, nurses, and surgeons, to gain a frontline perspective of perioperative practice realities.

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The use of chemotherapeutics has achieved considerable success in cancer therapy; however, their toxicity can severely impact patients' health. In this study, aiming to reduce the doses and potential side effects of traditional chemotherapeutics, we systematically treated A375MM human melanoma cells with seven clinically approved antineoplastic drugs, in combination with three well-characterized G-quadruplex (G4) ligands, using either simultaneous or sequential dosing schedules. Interestingly, the G4 binders synergized with most of the investigated anticancer drugs, with the degree of synergism being strictly dependent on both the treatment schedule and the drug sequence employed.

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Article Synopsis
  • The study investigated tick-borne rickettsial bacteria in ticks collected from stray dogs in the Patagonian region of Argentina.
  • A total of 90 ticks were examined, with 3 out of 33 tick pools testing positive for Anaplasmataceae bacteria, and partial DNA sequences confirming the presence of a bacteria linked to canine cyclic thrombocytopenia.
  • Additionally, two tick samples were identified as part of the spotted fever group rickettsiae, marking the first molecular detection of these pathogens in this area of Argentina.
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