Double extreme-cum-median ranked set sampling.

Extreme-cum-median ranked set sampling has been developed to address the problem of heterogeneity and outliers / extreme values. Double ranked set sampling has been suggested to obtain more reliable samples using the concept of degree of distinguishability. Dealing with heterogeneous and non-normal populations seems to be an area with a dearth of research.

New 4-amino-3-chloro benzoate ester derivatives as EGFR inhibitors: synthesis, in silico and biological analyses.

Aim: The main goal of this study was to synthesize new derivatives of 4-amino-3-chloro benzoate ester, including 1,3,4-oxadiazole derivatives (), benzohydrazone derivatives (), and hydrazine-1-carbothioamide derivatives () that target epidermal growth factor receptor (EGFR) tyrosine kinase.

Materials & Methods: The new derivatives were characterized using various spectroscopic techniques. Docking studies were used to investigate the binding patterns to EGFR, and the anti-proliferative properties were tested in vitro.

Hypercalcemic Ovarian Carcinoma (Small Cell Carcinoma of the Ovary, Hypercalcemic Type (SCCOHT)): A Case Series and Review of Literature of a Rare Malignancy.

Small cell carcinoma of the ovary, hypercalcemic type (SCCOHT) is one of the rare and aggressive cancers occurring mainly in adolescents and young women. It accounts for less than 0.01% of all ovarian malignancies, with around 500 cases reported to date in the medical literature.

Lignocellulosic fiber reinforcement in PPRC composites: An analysis of structural and thermal enhancements.

This study investigates the fabrication process of biocomposites and their resultant mechanical and thermal properties, essential for evaluating the performance of finished products. Polypropylene random copolymer (PPRC) was employed as the matrix phase, while rice husk (RH), a biowaste filler, was incorporated in varying concentrations. The rice husk fiber was treated with alkali (RHT) to enhance its lignocellulosic content.