[The extent of coronary stenosis and the level of antibodies to atherogenic lipoproteins in patients with coronary heart disease].

Aim: To study association between the level of antibodies to oxidized low-density lipoproteins (anti-OLDL) and the extent of coronary stenosis (CS) in patients with coronary heart disease (CHD).

Material And Methods: Sixty CHD patients were examined for titer of anti-OLDL, levels of total cholesterol (TC), LDLP cholesterol, HDLP cholesterol, triglycerides. Selective coronarography (SC) was made on demand.

[Antiphospholipid activity of the blood in patients with ischemic heart disease and thrombogenic complications].

The authors propose a method of estimating antiphospholipid activity of blood by phospholipids (PL) assays in circulating immune complexes (CIC). Screening of PL in CIC is an additional test in examination of patients with ischemic heart disease associated with thrombogenic complications and suspected antiphospholipid syndrome.

[Influenza virus infection in progressing atherosclerosis].

Aim: To study relationship between influenza virus infection and activity of clinical presentations of atherosclerosis.

Methods And Results: Average blood level of IgG to influenza A virus was significantly higher in patients with progressing forms of ischemic heart disease then in patients without objective signs of exacerbation of atherosclerotic process. Mean titles of antibodies to parainfluenza virus and adenoviruses were similar in both groups of patients.

[Pathogenetic significance of cholesterol-containing immune complexes and lipid peroxidation in ischemic heart disease].

Aim: To ascertain a relationship between cholesterol content in circulating immune complexes (CIC) and plasm lipid peroxidation (LPO) in patients with ischemic heart disease (IHD).

Materials And Methods: Blood samples from 33 IHD patients 23 of which had a history of myocardial infarction and from 8 healthy subjects were examined for total cholesterol, high and low density lipoproteins cholesterol, CIC, the ability of blood serum to induce free radicals, superoxide dismutase.

Results: A statistically significant positive correlation was found between CIC cholesterol level and content of free radicals while a negative correlation existed between superoxide dismutase activity and high density lipoprotein cholesterol level in blood plasm of healthy individuals and patients with IHD.