Publications by authors named "S A Tirelli"
Background: Like other parts of the body, the retina and its neurovascular system are also affected by age-related changes. The rising age of populations worldwide makes it important to study the pathologies related to age and their potential risk factors, such as diet and eating habits. The aim of this study was to investigate the predictive power of food groups versus retinal features among noninstitutionalized older adults from Southern Italy using a machine learning approach.
View Article and Find Full Text PDFGrowing evidence suggests that inflammation contributes to brain aging and neurodegeneration. This study investigates the relationship between global cognitive as well executive function and the inflammatory markers IL-6, CRP, and TNF-α in a population-based study of older adults. A population-based sample, of older people in Southern Italy, was enrolled.
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- The study examines the relationship between retinal health and liver fibrosis in older adults, highlighting the need for further exploration of this connection.
- Using optical coherence tomography (OCT) and OCT-angiography (OCT-A) to assess retinal features, the study correlates these findings with liver fibrosis risk, measured by the fibrosis-4 (FIB-4) score.
- Results show that thicker gangliar cell complexes in the retina are linked to lower FIB-4 scores, suggesting a relationship between retinal neurodegeneration and liver health, which opens up new research avenues regarding diagnostic tools for liver disease.