The results of morphological investigations of relapsing myocardial infarction in 148 rabbits are presented. In most cases the relapses occurred spontaneously at intervals of several to 45 days after reproduction of the primary myocardial infarction by high ligation of the anterior interventricle artery of the heart. It was found that relapses of myocardial infarction could develop in animals normal before the experiment (I series), against the background of cholesterol atherosclerosis (II series), renal hypertension (III series) and particularly frequently in combinations of cholesterol atherosclerosis and renal hypertension (IV series) as well as after repeated delayed ligation of the anterior interventricle artery (V series).
View Article and Find Full Text PDFThe morpho-functional features of peripheral blood leukocytes were studied in 50 rabbits with experimental myocardial infarction at various intervals after ligation of the anterior interventricle artery. Changes in the leukocytes were compared with the morphological picture of myocardial infarction. In the acute period of experimental myocardial infarction not only quantitative changes were found to occur but also functional values of leukocytes changes: the content of glycogen and the activities of peroxidase and phagocytic activity of granulocytes were reduced, while the activity of alkaline phosphatase increased.
View Article and Find Full Text PDF