Publications by authors named "S A Strauss"

Article Synopsis
  • * It emphasizes that any bone pain or noticeable mass should prompt further investigation, and patients with suspected primary bone tumours must be referred to specialized centres for care by accredited teams.
  • * The guidelines outline effective treatment options for various tumour types, including strategies for localized, metastatic, and recurrent disease, along with recommended follow-up schedules.
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The retina extracts chromatic information present in an animal's environment. How this information is processed in the retina is not well understood. In the mouse, chromatic information is not collected equally throughout the retina.

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Article Synopsis
  • Metastatic disease is a major cause of cancer-related deaths, yet its tumor microenvironment is not well understood due to technical challenges in studying it.
  • This research created a comprehensive map of 67 tumor biopsies from 60 metastatic breast cancer patients, using advanced techniques like single-cell RNA sequencing and various spatial expression assays to analyze tumor characteristics.
  • Key findings included identifying different macrophage spatial patterns, three phenotypes of epithelial-to-mesenchymal transition, and gene expression linked to T cell presence or absence, highlighting the study's potential for clinical insights.
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Background: Fatigue and sleep disorders are prevalent in cancer patients. Obstructive sleep apnea (OSA) commonly causes excessive daytime sleepiness (EDS) and fatigue. We hypothesize that treating cancer patients with OSA using positive airway pressure (PAP) will improve EDS and fatigue.

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Article Synopsis
  • The study examined brain connectivity in 51 CRPS patients compared to 50 control subjects, finding both weak and some specific differences in functional connectivity.
  • It highlighted lower connectivity between the periaqueductal gray matter and the anterior insula, and higher connectivity within the reward system, indicating potential mechanisms in CRPS pain modulation.
  • Importantly, the researchers observed lower data quality in CRPS patients, suggesting that findings on connectivity should be re-evaluated in future studies for better reliability.
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