Dementia Care Research and Psychosocial Factors.

Background: Research on cognitive reserve (CR) in individuals aged 80 years old and above has resulted in inconsistent findings, mostly showing a relationship with baseline cognitive abilities but not follow up assessments. The effects of amyloid burden on the relationship between CR, cognitive decline and dementia in oldest old warrants further study in the presence of APOE e4. We hypothesised that CR in oldest old (≥80 yrs old) adults will result in different trajectories, depending on being amyloid PET positive or negative.

Dementia Care Practice.

Background: Cognitive impairment is frequently undetected or undiagnosed in the early stages. To increase the rates of detecting cognitive impairment, the Early Detection program of the Davos Alzheimer's Collaborative System Preparedness (DAC-SP) implemented digital cognitive assessments (DCA) in primary care and other non-specialty settings.

Methods: The DAC-SP Early Detection program was initiated in 2021 in seven healthcare systems across six countries.

Melanoma Among Adult Survivors of Childhood Cancer: A Report From the Childhood Cancer Survivor Study.

Purpose: Melanoma as a subsequent malignant neoplasm has been described among childhood cancer survivors; however, the risk factors and long-term survival are not well understood.

Methods: We assessed incidence, risk factors, and outcomes for melanoma among participants in the Childhood Cancer Survivor Study cohort. Cumulative incidence and standardized incidence ratios (SIRs) were calculated, and multivariable Cox models were used to determine hazard ratios (HRs) and associated 95% CI for melanoma risk factors.

Investigation and Treatment of Infertility in a Female Black Rhinoceros (Diceros bicornis).

A zoo-based, 11-year-old, uniparous southern black rhinoceros (Diceros bicornis minor) failed to conceive after weaning a calf. Behavioral observation and fecal progestagen monitoring confirmed irregular estrous cycles. Serial transrectal reproductive ultrasound examination revealed the cause to be recurrent anovulatory hemorrhagic follicles (AHFs).

Exposing the obscured influence of state-controlled media via causal inference of quotation propagation.

Reporting by major media outlets influences news coverage by other outlets, resulting in an outsized impact on public opinion. Understanding this inter-outlet influence, known as intermedia agenda setting, is important for assessing the impact of state media and strategic communications. We demonstrate a novel method to quantify inter-outlet influence using causal inference on "quote following," where one outlet uses the same quote as another outlet at a later date.