[Diagnostic value of Diamed AG latex gel kit for detection of diphtheria toxin].

ID-PaGIA diphtheria toxin polymer particle diagnostic agent manufactured by DiaMed AG, Switzerland, was tried at bacteriological laboratory of Institute of Childhood Infections in St. Petersburg. The trials were carried out using two methods, direct and capture, which differ by the duration of incubation of the studied C.

[Methods of autologous peripheral blood stem cell (PBSC) mobilization in oncological and hematological patients].

The potential of peripheral blood stem cell (PBSC) mobilization with granulocyte (G-CSF) and granulocyte-macrophage (GM-CSF) colony-stimulating factors of chemotherapy has been assessed in patients with tumor or hematological disease. The study was intended to aid PBSC transplantation. It was shown that G-CSF administration increased the number of leukocytes in leukemia patients dramatically while mononuclear cell and colony-forming unit levels in G-CSF-mobilised PBSC were significantly higher than those collected with GM-CSF or chemotherapy.

[The transfusion aspects of allogeneic bone marrow transplantation].

Aim: Analysis of transplantations of allogenic bone marrow (BM) for determination of transfusiological problems arising in various types of donor's and recipient's blood ABO incompatibility.

Materials And Methods: 46 allogenic BM transplantations from relative donors are analysed. The following types of ABO incompatibility were identified: significant (12 donor-recipient pairs), insignificant (10 pairs), combined (2 pairs).

[The transplantation of hemopoietic cells in patients with solid tumors].

Aim: Evaluation of efficiency of bone marrow and peripheral stem cells transplantation in patients with solid tumors.

Materials And Methods: A total of 38 patients aged 30-40 years with stage III or IV solid tumors (15 cases of breast cancer, 5 cases of Ewing's sarcoma, 4 cases of osteogenic sarcoma, ovarian or testicular tumors, 3 cases of soft tissue sarcoma) underwent high-dose polychemotherapy with autologous hematopoietic rescue. All the patients were resistant to the first line chemotherapy or were in relapse of the disease.

[Analysis of the work of an analgesia service in an outpatient clinic].

The management of patients with chronic pain syndrome in out-patient clinics is a new form of specialized therapy. 347 cancer patients were treated using a modified "analgetic staircase" technique (14% of them at home), with an analgetic effect achieved in 60-70% of cases. The patients with pain syndrome were managed using sacral, epidural and subarachnoidal neurolysis blockades.