Biomarkers.

Background: African American (AA) persons have a higher Alzheimer's disease (AD) prevalence and report more perceived stress than White persons. Our previous cross-sectional study (JAD, 2020, 77:843-853) demonstrated an association between self-reported stress levels and cerebrospinal fluid (CSF) AD biomarkers. Using a biracial cohort, the current study investigates the association between stress and longitudinal CSF AD biomarkers over time.

Biomarkers.

Background: Older African American (AA) and Hispanic American (HA) adults have a higher risk for Alzheimer's disease and related dementias (ADRD) compared to non-Hispanic white (NHW) adults. AA and HA persons may also develop disease at younger ages with more rapid progression. Vascular disease, including cerebral small vessels, manifest by white matter hyperintensity (WMH) lesions, is more prevalent in AA and HA.

Biomarkers.

Background: Older African American (AA) and Hispanic American (HA) adults have a higher risk for Alzheimer's disease (AD) than older non-Hispanic white (NHW) adults. Cerebrovascular disease reflected by white matter hyperintensity (WMH) lesions on magnetic resonance imaging (MRI) may influence ADRD risk in these groups. Amyloid and tau PET data from studies of mostly NHW participants show a relationship between AD pathology and WMH lesions.

Biomarkers.

Background: Older African American (AA) and Hispanic American (HA) adults have a higher risk for Alzheimer's disease and related dementias (ADRD) than older non-Hispanic white (NHW) adults. Adverse experiences like stress and discrimination may contribute to the higher vascular disease burden observed in AA and HA persons. Cerebrovascular disease reflected by white matter hyperintensity (WMH) lesions on magnetic resonance imaging (MRI) may affect ADRD risk in older AA and HA adults.

Creativity research in medicine and nursing: A scoping review.

Background: Creativity fuels societal progress and innovation, particularly in the field of medicine. The scientific study of creativity in medicine is critical to understanding how creativity contributes to medical practice, processes, and outcomes. An appraisal of the current scientific literature on the topic, and its gaps, will expand our understanding of how creativity and medicine interact, and guide future research.