Publications by authors named "S A Salami"
Sleep is a vital biological function that significantly influences overall health. While sleep deprivation (SD) and circadian rhythm disruption are known to negatively impact various organs, their specific effects on kidney function remain understudied. This study aimed to investigate the impact of chronic partial sleep deprivation and circadian rhythm disruption on renal function in rats, providing insights into the relationship between sleep disturbances and kidney health.
View Article and Find Full Text PDFBackground And Objective: Prostate cancer (PC) in the transition zone (TZ) has better prognosis than peripheral-zone (PZ) PC despite higher prostate-specific antigen (PSA) in patients with TZ tumors. Our aim was to characterize molecular differences between TZ and PZ tumors and their clinical implications.
Methods: We performed spatial whole-transcriptome analyses of 50 regions of interest (ROIs) from three patients with PZ and/or TZ PC.
Quality of life of primary caregivers of autistic children: Structural equation modeling.
J Pediatr Nurs
November 2024
Purpose: Because autistic children may face difficulties living independently, considering their caregivers' quality of life (QoL) is crucial. However, few studies have examined the pathways through which the severity of autism spectrum disorder (ASD) affects caregivers. Based on the stress process model, this study examined a hypothesized model of how ASD severity affects caregivers' QoL, both directly and indirectly, through coping strategies, family functioning, and perceived social support.
View Article and Find Full Text PDFArticle Synopsis
- There is growing recognition that prostate cancer patients often have germline variants that can have significant implications for their health and that of their families, necessitating a deeper understanding of which individuals may carry these variants.
- A study involving 505 prostate cancer patients was conducted, tracking various factors and evaluating the presence of pathogenic or likely pathogenic (P/LP) germline variants through genetic testing aligned with NCCN guidelines.
- The study found that the occurrence of P/LP variants was similar across different age groups and clinical characteristics, with only the age at testing in metastatic patients showing a predictive association for these variants, indicating challenges in refining existing clinical guidelines.