Publications by authors named "S A Rizwan"
Recently, a novel class of emerging 2D materials identified as MXene have been revolutionizing the fabrication and development of flexible energy storage systems, i.e., batteries and supercapacitors.
View Article and Find Full Text PDFNew therapeutic agents developed for treating neurological disorders are often tested successfully on rodents. Testing in an appropriate large animal model where there is longer lifespan and comparable brain size to humans should improve translational success and is frequently expected by regulatory bodies. In this project, we aimed to establish a novel sheep model of Parkinson's disease as a large-brained experimental model for translational research.
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- Non-tobacco products (NTP) are gaining popularity as alternatives to traditional tobacco, but there's growing concern about their potential health risks, particularly regarding oral, esophageal, and pharyngeal cancers.
- A systematic review analyzed 49 studies involving over 132,000 participants, showing a significant increase in cancer risk associated with NTP use, with odds ratios indicating a 5x risk for oral cancer and 3x for esophageal cancer.
- The review emphasizes the need for greater regulation and awareness, as NTP use accounts for a considerable proportion of cancer cases, urging the inclusion of NTP data in national health surveys to better address the issues in high-risk groups.
Metabolic Phenotyping of Healthy and Diseased Human RPE Cells.
Invest Ophthalmol Vis Sci
September 2024
Purpose: Metabolic defects in the retinal pigment epithelium (RPE) underlie many retinal degenerative diseases. This study aims to identify the nutrient requirements of healthy and diseased human RPE cells.
Methods: We profiled nutrient use of various human RPE cells, including differentiated and dedifferentiated fetal RPE (fRPE), induced pluripotent stem cell-derived RPE (iPSC RPE), Sorsby fundus dystrophy (SFD) patient-derived iPSC RPE, CRISPR-corrected isogenic SFD (cSFD) iPSC RPE, and ARPE-19 cell lines using Biolog Phenotype MicroArray Assays.
Marine organisms produce a variety of compounds with pharmacological activities. In order to better comprehend the medicinal value of five particular seaweed orders Ulvales (Ulva intestinalis), Bryopsidales (Codium decorticatum), Ectocarpales (Iyengaria stellata), Dictyotales (Spatoglossum aspermum) and Gigartinales (Hypnea musciformis), a bioactive analysis including the screening of phytochemical components, antioxidant and antimicrobial activities was the aim of the investigation. The species include U.
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