A non-inferiority analysis of surgical outcomes following outpatient laminoplasty for cervical spondylosis.

Objective: A trend of outpatient spinal procedures has recently been observed due to evidence of less hospital-associated risks and better value-based care. We aimed to assess non-inferiority in surgical outcomes of outpatient and inpatient laminoplasty for cervical spondylosis.

Methods: The American College of Surgeons National Surgical Quality Improvement Program database was queried for patients undergoing cervical laminoplasty for spinal spondylosis.

Srcap Loss Alters H2A.Z-Dependent and Neuronal Differentiation-related Gene Expression in N2A Cells.

The chromatin remodeler SRCAP plays a critical role in depositing the histone variant H2A.Z, which is essential for transcriptional regulation, chromatin accessibility, and neurodevelopmental processes. Despite its known importance, the mechanisms by which SRCAP regulates H2A.

Research prioritisation in preparedness for and response to outbreaks of high-consequence pathogens: a scoping review.

Background: Priority setting for research on epidemic/pandemic-prone pathogens is essential for the allocation of limited resources to optimise impact. It involves the identification of gaps in knowledge crucial to effective preparedness and response to outbreaks. This review maps priority-setting exercises, reviews their approaches to research prioritisation and describes associated monitoring and evaluation processes for research priorities on high-consequence pathogens.

Perceptions of the Black population on fertility care: A scoping review.

Assisted reproductive technologies (ART), such as in vitro fertilization (IVF), offer hope for people struggling with infertility. Studies demonstrate that disparities in access and experiences with fertility care exist among different racial groups, particularly affecting Black women. This scoping review aims to explore Black women's perceptions of fertility care and psychosocial barriers that they encounter when accessing care.

DHUpredET: A Comparative Computational Approach for Identification of Dihydrouridine Modification Sites in RNA Sequence.

Laboratory-based detection of D sites is laborious and expensive. In this study, we developed effective machine learning models employing efficient feature encoding methods to identify D sites. Initially, we explored various state-of-the-art feature encoding approaches and 30 machine learning techniques for each and selected the top eight models based on their independent testing and cross-validation outcomes.