Publications by authors named "S A Pyxaras"
Background: Abbreviated antiplatelet therapy (APT) reduces bleeding without increasing ischemic events in largely unselected high bleeding risk (HBR) patients undergoing percutaneous coronary intervention (PCI). Diabetes mellitus (DM) is associated with higher ischemic risk, and its impact on the safety and effectiveness of abbreviated APT in HBR PCI patients remains unknown.
Objectives: This study sought to investigate the comparative effectiveness of abbreviated (1 month) vs standard (≥3 months) APT in HBR patients with and without DM after biodegradable polymer sirolimus-eluting coronary stent implantation.
Article Synopsis
- The CTO-ARC identified the need for standardized definitions in chronic total occlusion (CTO) procedures to avoid bias in attributing complications to different crossing strategies.
- A study analyzed data from 8,673 patients in the European Registry of Chronic Total Occlusions, finding that the antegrade approach was used in 79.2% of cases, while retrograde was used in 20.8%.
- Results showed that alternative antegrade crossing had lower technical success rates and higher complication rates compared to true antegrade and retrograde methods, though it was primarily used as a rescue strategy in most instances.
Heart failure (HF) is a complex clinical syndrome associated with significant morbidity, mortality, and healthcare costs. It is characterized by various structural and/or functional abnormalities of the heart, resulting in elevated intracardiac pressure and/or inadequate cardiac output at rest and/or during exercise. These dysfunctions can originate from a variety of conditions, including coronary artery disease, hypertension, cardiomyopathies, heart valve disorders, arrhythmias, and other lifestyle or systemic factors.
View Article and Find Full Text PDF