[Receptor-mediated endocytosis of alpha 2-macroglobulin in living intact 3T3 cells].

Internalization process of the fluoresceinisothiocyanate-labeled alpha 2-macroglobulin (MG-F) in Swiss 3T3 cells has been studied. The presence of internalized MG-F, formation of endocytotic vesicles and endosomal pH value were estimated visually on living monolayer cells with TV microscope, on the base of supervidicon LI-702. The use of the TV method allowed to obtain a series of photographs of cell images without any significant dye fading.