Effect of naloxone hydrochloride on osteogenesis in chick embryos.

Naloxone hydrochloride, an opioid receptors blocker, was administered to chick embryos. Morphological analysis of femoral bones of embryos showed an appreciable increase in the thickness of the perichondral bone cuff in the tubular bone diaphyses and increased mitotic activity in the zone of proliferating young cartilage of the epiphyseal plate.

[Clinico-immunologic evaluation of the sequelae of closed craniocerebral injuries].

Sixty-four patients were examined clinically and immunologically at a long-term period following craniocerebral trauma. In patients with a history of head trauma impaired adaptation mechanisms were shown to underlie the neurologic disorders, which was reflected in changes in the natural immunity system. The severity and duration of natural resistance impairments were correlated with the gravity of clinical manifestations.