Publications by authors named "S A Nunn"

The Centers for Disease Control and Prevention (CDC) Science Clips is an online weekly bibliographical digest showcasing over 46,000 scientific articles and publications from 2009 to present. The digest is curated by the Stephen B. Thacker CDC Library to bring awareness to relevant and quality public health literature.

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Background: Breast cancer is a common and increasingly treatable disease. However, survivors have a significantly elevated risk of cardiac events afterwards. This study aimed to characterise cardiac changes during cardiotoxic cancer therapy using cardiovascular magnetic resonance (CMR) imaging.

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Background: As individual synthetic cathinones become scheduled and regulated by the Drug Enforcement Administration (DEA), new ones regularly are produced and distributed. One such compound is eutylone, a novel third-generation synthetic cathinone whose affective properties (and abuse potential) are largely unknown. The following experiments begin to characterize these effects and how they may be impacted by drug history (a factor affecting reward/aversion for other drugs of abuse).

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Article Synopsis
  • The study aimed to investigate the rewarding and aversive effects of drugs using a combined conditioned taste aversion (CTA) and place preference (CPP) method in mice, similar to previous findings in rats.
  • Male and female C57BL/6 mice were given a saccharin solution and injected with varying doses of a synthetic drug called methylone, followed by assessments of taste aversion and place preference after conditioning.
  • Results showed that mice developed significant taste aversion and place preference, indicating that the combined design is effective; however, there was no correlation between how much they avoided the taste and how much they preferred the location, suggesting independent pathways for these effects.
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