[Clinical efficacy of arbidol (umifenovir) in the therapy of influenza in adults: preliminary results of the multicenter double-blind randomized placebo-controlled study ARBITR].

Aim: To evaluate the efficacy and safety of Arbidol (umifenovir) in adult patients with influenza.

Subjects And Methods: The analysis of the preliminary results of the multicenter double-blind randomized placebo-controlled post-marketing study ARBITR was performed. A total of 293 adults aged 18 to 65 years with influenza or acute respiratory tract infection of no more than 36 hours' duration were enrolled in the study.

[The proinsulin level in the blood of children with type 1 diabetes mellitus of various duration].

Proinsulin content was measured in the serum of 82 children (aged from 3 to 14 years) with type 1 diabetes mellitus of various duration. Three groups of patients characterized by low (54%), normal (42%) and high (4%) levels of this prohormone were recognized. No dependence the proinsulin level on the disease term was found.

[Effect of afobazole on the psychophysiological state of healthy volunteers].

The influence of the selective anxiolytic drug afobazole in a single dose of 10 mg on the psychophysiological functions of healthy volunteers was studied in laboratory experiments. It is established that afobazole optimizes some psychophysiological characteristics of stress-labile individuals and has no negative influenceon the parameters of attention, psychomotor reaction a nd speed of decision making.

[Effect of ladasten on the psychophysiological parameters of healthy volunteers].

The ability of the antiasthenic drug ladasten (single dose, 100 mg) to influence psychophysiological functions was evaluated in laboratory experiments with participation of healthy volunteers. It was established that ladasten does not exhibit behavioral toxicity and improves psychophysiological parameters in the state of mental fatigue. The drug effects were more pronounced in stress-labile individuals.