Not "a cute" complication: phenotypic analysis of acute kidney injury in Staphylococcus aureus bacteraemia.

Objectives: In this large retrospective cohort analysis, we aimed to determine the incidence of Kidney Disease Improving Global Outcomes (KDIGO)-defined acute kidney injury (AKI) within 14 days in patients with Staphylococcus aureus bacteraemia (SAB), and the association of AKI with 30-day mortality.

Methods: A retrospective cohort study of adults with SAB between 1998 to 2023 admitted to a large regional Australian health service. Baseline creatinine was the lowest serum creatinine concentration in the 365 days before the day of index blood culture collection and AKI was defined and staged using the KGIDO criteria.

VRE acquisition in hospital and its association with hospital antimicrobial usage -a non-linear analysis of an extended time series.

Background: Vancomycin resistant enterococci (VRE) have become endemic pathogens in many Australian hospitals causing significant morbidity. There are few observational studies that have evaluated the effect of antibiotic usage on VRE acquisition. This study examined VRE acquisition and its association with antimicrobial use.

What gets measured gets noticed. Tracking surgical site infection post caesarean section through community surveillance: A post intervention study protocol.

Aim: This study aims to evaluate the effectiveness of HealthTracker, a surgical site infection surveillance system that aims to improve the notification of surgical site infection for women after giving birth by caesarean section.

Design: This protocol is an intervention study to evaluate the effectiveness of the surveillance system called "HealthTracker" in monitoring surgical site infections post caesarean section.

Methods: This study will use a mobile web application to automatically send a text message inviting all women who give birth to a live baby by caesarean section over six months during 2020-2021, at an Australian tertiary referral hospital.

Participant-Centered Online Active Surveillance for Adverse Events Following Vaccination in a Large Clinical Trial: Feasibility and Usability Study.

Background: Active participant monitoring of adverse events following immunization (AEFI) is a recent development to improve the speed and transparency of vaccine safety postmarketing. Vaxtracker, an online tool used to monitor vaccine safety, has successfully demonstrated its usefulness in postmarketing surveillance of newly introduced childhood vaccines. However, its use in older participants, or for monitoring patients participating in large clinical trials, has not been evaluated.