Publications by authors named "S A Malek-Hosseini"

Introduction: As far as it is known, long-lasting immunosuppressive therapy might put patients with solid organ transplantation (SOT) at increased risk for severe to profound sensorineural hearing loss, eventually leading to cochlear implantation (C.I). So, the main aim of the present study is to evaluate their auditory perception performance after cochlear implantation.

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The main purpose of this study was to compare the remineralizing effects of casein phosphopeptide amorphous calcium phosphate fluoride (CPP-ACPF) and tricalcium phosphate (TCP) on artificially induced enamel white spot lesions (WSLs). In this in vitro study, 45 sound extracted premolars were immersed in a demineralizing solution (pH=4.5) for 96 hours, and were randomly divided into 3 groups of TCP, MI Paste Plus, and control.

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Article Synopsis
  • Primary sclerosing cholangitis (PSC) is an autoimmune disease that affects bile ducts and can recur after liver transplantation, leading to serious complications like liver failure and reduced survival rates.
  • A study analyzed 408 patients who had liver transplants between 2011 and 2021, identifying lower donor age and acute cellular rejection episodes as significant risk factors for PSC recurrence.
  • The findings revealed that patients with recurrent PSC had a much higher death rate (40.8%) compared to those without recurrence (18.9%), highlighting the need for targeted strategies to manage these risk factors to improve post-transplant outcomes.
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Objectives: Thiopurine prodrugs are commonly used in kidney transplant recipients. Inosine triphosphate pyrophosphatase is an enzyme encoded by the ITPA gene. Alteration of ITPA gene is one of the pharmacogenetic sequence variants possibly involved in thiopurine metabolism.

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Background: Hepatic steatosis is an increasing complication in liver transplant recipients. Currently, there is no pharmacologic therapy for treatment of hepatic steatosis after liver transplantation. The aim of this study was to determine the association between use of angiotensin receptor blockers (ARB) and hepatic steatosis in liver transplant recipients.

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