Publications by authors named "S A M de Jongh"

Article Synopsis
  • There is currently no universally accepted method for titrating positive end expiratory pressure (PEEP) in patients on spontaneous mechanical ventilation (SMV), despite some success with electrical impedance tomography (EIT) in controlled mechanical ventilation.
  • A new approach using regional peak flow (RPF) via EIT aims to evaluate lung mechanics specifically for SMV, which was not effectively addressed by existing algorithms.
  • In a study of 25 COVID-19 ARDS patients, EIT-guided PEEP titration showed feasibility and suggested that a cumulative collapse threshold of around 5% could provide the best balance of clinical and mechanical outcomes.
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Article Synopsis
  • Flap necrosis is a common issue in autologous breast reconstruction, prompting a study on the benefits of indocyanine green angiography (ICGA) for evaluating flap perfusion.
  • The study involved 15 patients undergoing DIEP flap reconstruction, using ICGA, hyperspectral imaging (HSI), and thermal imaging (TI) to analyze flap perfusion and correlate findings with clinical outcomes.
  • Results indicated that ICGA effectively identified perfusion issues, while HSI showed promise for monitoring but TI had limited usefulness; further studies are needed to confirm the real-time clinical benefits of these imaging techniques.
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Purpose: To describe the effect of dexamethasone and tocilizumab on regional lung mechanics over admission in all mechanically ventilated COVID-19 patients.

Materials And Methods: Dynamic compliance, alveolar overdistension and collapse were serially determined using electric impedance tomography (EIT). Patients were categorized into three groups; no anti-inflammatory therapy, dexamethasone therapy, dexamethasone + tocilizumab therapy.

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Background: Spontaneous breathing efforts during mechanical ventilation are a widely accepted weaning approach for acute respiratory distress syndrome (ARDS) patients. These efforts can be too vigorous, possibly inflicting lung and diaphragm damage. Higher positive end expiratory pressure (PEEP) levels can be used to lower the magnitude of vigorous breathing efforts.

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Background: Electrical impedance tomography (EIT) visualises alveolar overdistension and alveolar collapse and enables optimisation of ventilator settings by using the best balance between alveolar overdistension and collapse (ODCL). Besides, the global inhomogeneity index (GI), measured by EIT, may also be of added value in determining PEEP. Optimal PEEP is often determined based on the best dynamic compliance without EIT at the bedside.

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