AWARENESS OF LYME DISEASE AMONG VOCATIONAL SCHOOL STUDENTS AND CHILDREN (TERNOPIL REGION, WESTERN UKRAINE).

The research goal is to assess the awareness of Lyme borreliosis among students and parents whose children were bitten by ticks (aged 3 to 18 years) and to inform about preventive measures that are carried out in case of contact with ticks in college students and bitten children in Ternopil region (Western region of Ukraine). The research was conducted by surveying 95 18-year-old first-year students of a vocational technical, and 78 parents whose children were bitten by ticks (children aged 3 to 18 years). Children of this group were treated for EM.

LYME BORRELIOSIS - ENDEMIC DISEASE IN CHILDREN OF TERNOPIL REGION.

The aim of research is to estimate the number of LB-infected ticks and to evaluate their LB pathogen's genotype in children with clinical suspicion of Lyme borreliosis in the Ternopil region, Ukraine. In our first part of the study we conducted survey of 795 patients with clinical suspicion of Lyme borreliosis. In our second study we did laboratory analysis of the 795 ticks and 109 blood samples from children that were bitten by a tick.

The Jarisch-Herxheimer reaction associated with doxycycline in a patient with Lyme arthritis.

Objectives: The objective of this article was to present the clinical peculiarity of the Jarisch-Herxheimer reaction (JHR) during antibiotic treatment of Lyme arthritis.

Material And Methods: Case study presentation as a basis for discussion, literature search of PubMed database particularly in the subject of combination of the JHR and Lyme borreliosis using the combination of words "Jarisch-Herxheimer reaction" and "Lyme borreliosis", "Lyme arthritis", "antibiotic treatment", "generalized inflammation", "cytokine production", "children", "increasing awareness"; discussion of the problem based on a clinical case and cited articles.

Results: The authors present a case of Lyme arthritis in a 13-year-old boy, as well as a discussion of clinical features of this complication of Lyme disease treatment as the Jarisch-Herxheimer reaction.

LABORATORY DIAGNOSTICS OF LYME BORRELIOSIS IN CHILDREN WITH TICKS BITES IN TERNOPIL REGION.

Lyme disease (systematic tick Borreliosis, Lyme Borreliosis, chronic erythema migrans) is a naturally-occurring disease caused by Borrelia burgdorferi, that manifests by migratory ring-shaped erythema, fever, affection of central and peripheral nervous system, heart and large joints. The aim of research was investigation the frequency of infection by Borrellia in children of Ternopil region . 150 children were examined, by interrogation and appropriate laboratory's examination.

[ROLE OF LEPTIN IN THE FORMATION OF SECONDARY AMENORRHEA IN ADOLESCENT GIRLS].

In order to understand the role of leptin in the formation of secondary amenorrhea (SA) during puberty, 78 girls aged from 13 to 17 years with SA and 74 girls of the same age with regular menstrual cycle have been examined with the estimation of body mass index (BMI) and hormonal/metabolic state. The obtained data show a strong connection between leptin level, BMI and parameters of energetic metabolic state (insulin; HOMA index); regression analysis results indicated the participation of leptin in steroidogenesis. Odds ratio (OR) values indicated an important role of leptin in the formation of SA during body weight deficit and normal BMI.