Effect of dutasteride treatment on reducing blood loss and in perioperative period of open prostatectomy.

Objective: Open prostatectomy (OP) is a valid option for the surgical treatment of large prostates in the absence of holmium laser enucleation. The most frequent complication of OP is intra- and perioperative bleeding. Preoperative use of dutasteride has been shown to reduce vascularity and perioperative bleeding in transurethral resection of the prostate (TUR-P).

Predictive factors for flexible ureterorenoscopy requirement after rigid ureterorenoscopy in cases with renal pelvic stones sized 1 to 2 cm.

Purpose: To evaluate the outcomes of rigid ureterorenoscopy (URS) for renal pelvic stones (RPS) sized 1 to 2 cm and to determine the predictive factors for the requirement for flexible URS (F-URS) when rigid URS fails.

Materials And Methods: A total of 88 patients were included into the study. In 48 patients, the RPS were totally fragmented with rigid URS and F-URS was not required (group 1).

[Effect of vibration on gamma-aminobutyric acid metabolism in the brain in various functional conditions of the adrenal cortex].

The low-frequency vibration during 30 min (20 Hz, A = 0.4 mm) has been studied for its influence on the level of components of the GABA system and dicarbonic ++amino acids in male rats at hypo- and hyperfunction of the adrenal cortex. It is shown that under these conditions of the experiment the GABA level and glutamate-decarboxylase activity increase.

[The effect of vibration on brain GABA metabolism in rats with hypo- and hypercalcemia].

The horizontal vibration (30 min, 20 Hz, A = 0.4 mm) has been studied for its influence on the level of GABA components and dicarbonic acids in brain tissues of adult male rats with hypo- and hypercalcemia. It is assumed, that hypercalcemia vibration situation prevents excessive stress agent, thus leading to a decrease in the level of GABA and activity of glutamate decarboxylase in various structures of the brain.