Publications by authors named "S A KHRUSTALEV"

During intraperitoneal administration of dispersiveness-comparable chrysotile or asbestos cement fibers to rats (20 mg thrice), mesotheliomas were found in 45.1 and 7.7% of cases respectively.

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Wistar rats were fed propoxur in their diet at 0, 500, 3000, and 8000 ppm during throughout their life. The number of tumors was equal in the control and experimental groups. These were hemoblastoses and breast and uterine tumors.

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When orally administered to rats and mice, phenol-free coal-tar creolin containing 0.018+/-0.002 g/kg of benz(a)pyrene showed no carcinogenic activity.

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The new drug thymodepressin was subcutaneously injected in doses 0.0145 and 0.145 mg/kg in rats and mice over a period of 104 weeks.

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Unlabelled: In telomerase-negative cell populations the mean telomere length (TL) decreases with increasing population doubling number (PD). A critically small TL is believed to stop cell proliferation at a cell-, age- and species-specific PD thus defining the Hayflick limit. However, positively skewed TL distributions are broad compared to differences between initial and final mean TL and strongly overlap at middle and late PD, which is inconsistent with a limiting role of TL.

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