Publications by authors named "S A Hashim"

Background: Semaglutide, a glucagon-like peptide-1, is an effective antidiabetic drug promoting weight loss and providing cardiovascular protection. The original trials did not include participants from Saudi Arabia; hence, the study's findings are expected to be useful.

Objectives: Explore the efficacy, safety, and favorable effects of once-weekly subcutaneous semaglutide (1 mg) in patients with type 2 diabetes and those who received it as an off-license prescription without having diabetes.

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Quality detection is critical in the development of prepared dishes, with distributional uniformity playing a significant role. This study used hyperspectral imaging (HSI) and Moran's I to quantify distributional uniformity, employing pizza as case. Pizza ingredients' spectra were collected, pre-processed with Detrended Fluctuation Analysis (DFA), Savitzky-Golay (SG) and Standard Normal Variate (SNV), and down-scaled with Principal Component Analysis (PCA).

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Objectives: Glaucoma is a leading cause of permanent blindness. Despite therapeutic advancements, glaucoma management remains challenging due to limitations of conventional drug delivery, primarily topical eye drops, resulting in suboptimal outcomes and a global surge in cases. To address these issues, liposomal drug delivery has emerged as a promising approach.

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Article Synopsis
  • Leber hereditary optic neuropathy (LHON) is a rare genetic disorder mainly affecting young men, leading to vision loss due to optic nerve degeneration, often misdiagnosed as optic neuritis.
  • A case study of an 18-year-old Malay male with a specific LHON mutation showed unexpected vision recovery over three years, highlighting the importance of genetic testing for accurate diagnosis and tracking potential outcomes.
  • The findings emphasize the significance of early diagnosis, genetic counseling, and supportive care in managing LHON, which can improve patients' quality of life despite the unpredictability of the condition.
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