Publications by authors named "S A Conrad"
Article Synopsis
- RORA is a gene linked to the development and function of the cerebellum, and this study explores the largest group of individuals with RORA-related neurodevelopmental disorders (RORA-NDD).
- The study involved 40 participants with various pathogenic variants of RORA, revealing a range of clinical features including developmental and intellectual disabilities, as well as cerebellar symptoms that can vary in onset and severity.
- Findings indicate that certain missense variants are associated with more severe cerebellar issues, and common elements of RORA-NDD include developmental disabilities, cerebellar symptoms, and different types of myoclonic epilepsy.
Objectives: This investigation aimed to examine the effects of the COVID-19 pandemic on treatment delays and the severity of initial disease presentation in cholesteatoma patients treated in the prepandemic and pandemic periods.
Methods: This retrospective cohort study was of patients who underwent primary surgical management of cholesteatoma between October 2018 and December 2021, split between the prepandemic (October 2018 to February 2020) and pandemic (April 2020 to December 2021) time periods. Data collected included time from referral to otology clinic visit, time of diagnosis, and time of surgical interventions.
ViViEchoformer: Deep Video Regressor Predicting Ejection Fraction.
J Imaging Inform Med
November 2024
Heart disease is the leading cause of death worldwide, and cardiac function as measured by ejection fraction (EF) is an important determinant of outcomes, making accurate measurement a critical parameter in PT evaluation. Echocardiograms are commonly used for measuring EF, but human interpretation has limitations in terms of intra- and inter-observer (or reader) variance. Deep learning (DL) has driven a resurgence in machine learning, leading to advancements in medical applications.
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- The text discusses the occurrence of dual circulation during venoarterial extracorporeal membrane oxygenation (VA-ECMO), where blood from the body and an artificial heart/lung system mix, resulting in differing oxygen and carbon dioxide levels in two separate circulations.
- This phenomenon arises when native blood flow from the heart meets retrograde blood flow from the artificial system, creating distinct physiological environments on either side of the mixing point.
- The authors aim to clarify the terminology surrounding this issue to improve communication and clinical management for patients undergoing VA-ECMO treatment.