Publications by authors named "S A Biliaminu"
Introduction: Human immunodeficiency virus HIV causes a well-known global disease, acquired immunodeficiency syndrome (AIDS), which has a high disease burden in Africa. HIV infection is known to be associated with oxidative stress, which may contribute to disease severity. However, the effect of HAART is equivocal, and requires more studies.
View Article and Find Full Text PDFThymoquinone ameliorate oxidative stress, GABAergic neuronal depletion and memory impairment through Nrf2/ARE signaling pathway in the dentate gyrus following cypermethrin administration.
BMC Neurosci
September 2024
Article Synopsis
- - The study investigates how thymoquinone can protect the brain from damage caused by the insecticide cypermethrin, focusing on its effects within the dentate gyrus region responsible for memory and motor functions.
- - Forty adult male rats were divided into five groups, receiving various treatments over 14 days, including combinations of cypermethrin and thymoquinone, followed by tests to assess memory and brain health.
- - Results indicate that thymoquinone improves memory performance and supports brain cell integrity while reducing neurotoxic effects of cypermethrin, suggesting its potential as a treatment for pesticide-related neurotoxicity.
Honey and levodopa comparably preserved substantia nigra pars compacta neurons through the modulation of nuclear factor erythroid 2-related factor 2 signaling pathway in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced Parkinson's disease model.
Anat Cell Biol
September 2024
Parkinson's disease (PD) affects about 8.5 million individuals worldwide. Oxidative and inflammatory cascades are implicated in the neurological sequels, that are mostly unresolved in PD treatments.
View Article and Find Full Text PDFBackground: Children with sickle cell disease (SCD) are at potential risk of iron overload from chronic transfusion and probable iron deficiency due to accelerated growth. However, only few studies on the iron status of children with SCD in Nigeria are available.
Methodology: A cross-sectional study compared the iron status of 109 children with sickle cell disease with 109 age and sex-matched haemoglobin AA controls at the University of Ilorin Teaching Hospital.
Background: Available information remains limited on inter-pregnancy interval (IPI) and its effect on maternal health and pregnancy outcome.
Objectives: To determine the effect of IPI on maternal serum ferritin, haematocrit and pregnancy outcome.
Materials And Methods: A prospective cohort study of 316 women categorized into WHO recommended IPI of ≥24 months (group I) and IPI <24 months i.